General
Preferred name
inosine
Synonyms
NSC 20262, INO 495 ()
Hypoxanthine riboside ()
Inotin ()
Inosina ()
Hypoxanthosine ()
INO-1001 ()
NSC-20262 ()
P&D ID
PD008719
CAS
12712-98-0
58-63-9
Tags
available
drug
Approved by
FDA
Drug Status
approved
experimental
investigational
Max Phase
3.0
Drug indication
viral disease
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Inosine is a nutritional supplement touted to improve athletic performance. It has anti-inflammatory, antinociceptive, immunomodulatory and neuroprotective effects. Inosine is an agonist for adenosine A1 and A2A receptors.
(Enamine Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
0
Compound Sets
16
Cayman Chemical Bioactives
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
Enamine Bioactive Compounds
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
52
Molecular Weight
268.08
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
4
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
2
cLogP
-2.27
TPSA
133.49
Fraction CSP3
0.5
Chiral centers
4.0
Largest ring
6.0
QED
0.48
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
PARP1, PNP
MOA
neurotrophic agent
Source data
