General
Preferred name
OXYPURINOL
Synonyms
Oxipurinol ()
NSC-76239 ()
P&D ID
PD008633
CAS
2465-59-0
465-59-0
Tags
available
drug candidate
Drug indication
Congestive heart failure
Heart failure
Drug Status
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Oxipurinol (Oxipurinol), the major active metabolite of Allopurinol, is an inhibitor of xanthine oxidase. Oxipurinol can be used to regulate blood urate levels and treat gout[1].
PRICE 29
DESCRIPTION Oxypurinol is a xanthine oxidase inhibitor. Oxipurinol is potentially used for the treatment of congestive heart failure. (TargetMol Bioactive Compound Library)
Compound Sets
13
AdooQ Bioactive Compound Library
A13431
Cayman Chemical Bioactives
18716
ChEMBL Drugs
CHEMBL859
Drug Repurposing Hub
DrugBank
DB05262
DrugMAP
DMURH4X
DrugMatrix
Enamine BioReference Compounds
EU-OPENSCREEN Bioactive Compound Library
EOS100225
MedChem Express Bioactive Compound Library
HY-19657
ReFrame library
Selleckchem Bioactive Compound Library
oxypurinol
TargetMol Bioactive Compound Library
T1694
External IDs
45
Properties
(calculated by RDKit )
Molecular Weight
152.03
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
3
Rotatable Bonds
0
Ring Count
2
Aromatic Ring Count
2
cLogP
-1.06
TPSA
94.4
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.45
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
Xanthine oxidase
XO
XDH
Drug Metabolite
ROS
MOA
ROS inhibitor
Xanthine Oxidase inhibitor
Pathway
Immunology/Inflammation
Metabolism
Metabolic Enzyme/Protease
Source data