General
Preferred name
LEUCINE
Synonyms
(S)-Leucine ()
Leu ()
L-leucine ()
(S)-Leucine, Leu ()
Leucine, l ()
E641 ()
NSC-46709 ()
FEMA NO. 3297 ()
L-Leucine-d10 ()
P&D ID
PD008452
CAS
61-90-5
25248-98-0
21675-61-6
71000-80-1
70-45-1
106972-44-5
Tags
natural product
drug
available
Approved by
FDA
Drug indication
Discovery agent
Amino Acid
Drug Status
nutraceutical
investigational
approved
Max Phase
Phase 3
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
18
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
Enamine BioReference Compounds
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
NPC Screening Collection
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
72
Properties
(calculated by RDKit )
Molecular Weight
131.09
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
0
Aromatic Ring Count
0
cLogP
0.44
TPSA
63.32
Fraction CSP3
0.83
Chiral centers
1.0
Largest ring
0.0
QED
0.58
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
PI3K/Akt/mTOR
Metabolic Enzyme/Protease
Target
MTOR
BCAT1, BCAT2, LARS, LARS2, LCMT1, LCMT2
Endogenous Metabolite
MOA
mTOR
Source data
