General
Preferred name
(S)-AMPA
Synonyms
L-AMPA ()
P&D ID
PD008185
CAS
83643-88-3
Tags
drug candidate
natural product
available
Drug indication
Discovery agent
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
NMDA partial agonist/antagonist; acts at glycine site
(Tocris Bioactive Compound Library)
DESCRIPTION
Selective AMPA agonist. Active isomer of (RS)-AMPA (Cat. No. 0169)
(Tocriscreen Total)
DESCRIPTION
(S)-AMPA is an active enantiomer of AMPA, which has been found to be a definitive agonist of the AMPA glutamatergic ionotropic receptor.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
8
BOC Sciences Bioactive Compounds
Drug Repurposing Hub
DrugBank
DrugMAP
MedChem Express Bioactive Compound Library
Tocris Bioactive Compound Library
Tocriscreen Total
ZINC Tool Compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
24
Molecular Weight
186.06
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
3
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
1
cLogP
-0.36
TPSA
109.58
Fraction CSP3
0.43
Chiral centers
1.0
Largest ring
5.0
QED
0.59
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Primary Target
AMPA Receptors
MOA
Agonist
glutamate receptor agonist
Target
GRIA2, GRIN1
iGluR
Pathway
Membrane Transporter/Ion Channel
Neuronal Signaling
Source data
