General
Preferred name
symmetric dimethylarginine
Synonyms
NG,NG'-Dimethyl-L-arginine ()
SDMA ()
P&D ID
PD008065
CAS
30344-00-4
Tags
available
drug candidate
Drug Status
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION SDMA (Symmetric dimethylarginine) is an endogenous inhibitor of nitric oxide (NO) synthase activity. SDMA, a novel kidney biomarker, permits earlier diagnosis of kidney disease than traditional creatinine testing.
PRICE 29
DESCRIPTION SDMA (Symmetric dimethylarginine) is the most potent endogenous inhibitor of nitric oxide synthase (NOS), with higher levels in patients with end-stage renal disease (ESRD). (TargetMol Bioactive Compound Library)
Compound Sets
5
DrugBank
DB02302
Guide to Pharmacology
5271
MedChem Express Bioactive Compound Library
HY-101410
Selleckchem Bioactive Compound Library
sdma
TargetMol Bioactive Compound Library
T7344
External IDs
35
Properties
(calculated by RDKit )
Molecular Weight
202.14
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
4
Rotatable Bonds
5
Ring Count
0
Aromatic Ring Count
0
cLogP
-1.03
TPSA
99.74
Fraction CSP3
0.75
Chiral centers
1.0
Largest ring
0.0
QED
0.26
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
Human Endogenous Metabolite
NO Synthase
Pathway
Immunology/Inflammation
Metabolic Enzyme/Protease
NF-κB
Metabolism
NF-¦ÊB
Source data