General
Preferred name
(R)-BICALUTAMIDE
Synonyms
BICALUTAMIDE ()
P&D ID
PD007946
CAS
90357-06-5
113299-40-4
Tags
drug candidate
available
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
(R)-Bicalutamide is the (R)-enantiomer of Bicalutamide (HY-14249). (R)-Bicalutamide is an androgen receptor (AR) antagonist, with antineoplastic activity. (R)-Bicalutamide is widely used for the research of prostate cancer[1][2].
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
7
Organisms
0
Compound Sets
4
DrugBank
MedChem Express Bioactive Compound Library
NPC Screening Collection
NURSA ligand set
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
26
Molecular Weight
430.06
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
5
Ring Count
2
Aromatic Ring Count
2
cLogP
2.88
TPSA
107.26
Fraction CSP3
0.22
Chiral centers
1.0
Largest ring
6.0
QED
0.56
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Vitamin D Related/Nuclear Receptor
Target
Androgen Receptor
Source data
