General
Preferred name
STEARIC ACID
Synonyms
Cetylacetic acid ()
Octadecanoic acid ()
Octadecanoic acid, Isostearic acid, Cetylacetic acid ()
Pristerene 4916 ()
Fatty acids, hydrogenated tallow ()
Neo-fat 18-57 ()
Sterene 60r ()
Hyfac 410 ()
Hydrogenated tallow fatty acids ()
Century 1210 ()
NSC-25956 ()
Tallow fatty acids, hydrogenated ()
Hystrene 7018 ()
Stearic acid 70 ()
Hydrogenated tallow acid ()
Hydrofol acid 150 ()
Prifac 5905 ()
Tallow, hydrogenated fatty acids ()
Pristerene 4910 ()
Stearate ()
Adeka sa 300 ()
Sterene 60b ()
N-octadecanoic acid ()
Neo-fat 18-58 ()
Hyfac 421 ()
Hydrogenated tallow acids ()
Tallow, acids, hydrogenated ()
Sterene 460 ()
Stearic acid 50 ()
Hydrogenated tallow acid, beef ()
Palmitostearic acid ()
FEMA NO. 3035 ()
Hyfac 422 ()
Dervacid 3155 ()
Kolliwax s fine ()
Pristerine 4989 ()
Hyfac 420 ()
Barolub fta ()
Edenor htict-n ()
NSC-261168 ()
Pristerene 4981 ()
E570 ()
Tallow acid, hydrogenated ()
Purified stearic acid ()
Stearic Acid-d35 ()
Stearic Acid-13C ()
Stearic Acid-d2 ()
Stearic Acid-9,10-d2 ()
Stearic Acid-d4 ()
Stearic Acid-d5 ()
P&D ID
PD007733
CAS
609343-71-7
68937-76-8
134503-33-6
57-11-4
126539-56-8
17660-51-4
85541-42-0
19905-58-9
57396-97-1
130048-57-6
211443-83-3
Tags
available
nuisance
drug
Approved by
FDA
Drug Status
approved
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
TOXICITY Acute oral toxicity (LD50): 4640 mg/kg [Rat]. Acute dermal toxicity (LD50): >5000 mg/kg [Rabbit].; ;
DESCRIPTION Stearic acid is a long-chain dietary saturated fatty acid that can significantly reduce visceral fat by inducing apoptosis of preadipocytes. Stearic acid can be used in the study of cardiovascular and metabolic diseases[1].
PRICE 90
DESCRIPTION Stearic acid is one of the useful types of saturated fatty acids that comes from many animal and vegetable fats and oils. It is used as an ingredient found in topical products as a skin protectant. (Enamine Bioactive Compounds)
DESCRIPTION 1. Stearic acid (Cetylacetic acid) can reduce metastatic tumor burden. 2. Stearic acid leads to dramatically reduced visceral fat likely by causing the apoptosis of preadipocytes. 3. Stearic acid and its derivatives have been used as gelators in food and pharmaceutical gel formulations. 4. Stearic acid is a potent phosphatase 1B inhibitor, possibly causing an enhancement in the insulin receptor signaling to stimulate glucose uptake into adipocytes. 5. Stearic acid has the potential to increase dry matter intake and yields of milk and milk components, without affecting conversion of feed to milk, body condition score, or body weight. (TargetMol Bioactive Compound Library)
Compound Sets
18
Cayman Chemical Bioactives
10011298
9003318
28917
28150
30549
28868
9000455
ChEMBL Drugs
CHEMBL46403
Concise Guide to Pharmacology 2017/18
3377
Concise Guide to Pharmacology 2019/20
3377
Concise Guide to Pharmacology 2021/22
3377
Concise Guide to Pharmacology 2023/24
3377
DrugBank
DB03193
DrugBank Approved Drugs
DB03193
DrugCentral
4611
DrugCentral Approved Drugs
4611
Enamine Bioactive Compounds
EBC-26446
Guide to Pharmacology
3377
MedChem Express Bioactive Compound Library
HY-B2219
NPC Screening Collection
Nuisance compounds in cellular assays
Selleckchem Bioactive Compound Library
stearic-acid
TargetMol Bioactive Compound Library
T2P2923
ZINC Tool Compounds
ZINC000004978673
External IDs
88
Properties
(calculated by RDKit )
Molecular Weight
284.27
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
16
Ring Count
0
Aromatic Ring Count
0
cLogP
6.33
TPSA
37.3
Fraction CSP3
0.94
Chiral centers
0.0
Largest ring
0.0
QED
0.34
Structural alerts
1
Surfactant
Nuisance compounds
Related compounds
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
Tyrosine Phosphatase 1B
Apoptosis
MOA
Tyrosinase
Pathway
Metabolism
Metabolic Enzyme/Protease
Source data