General
Preferred name
sorbinil
Synonyms
NSC-355082 ()
CP-45634 ()
CP-45,634 ()
P&D ID
PD007698
CAS
68367-52-2
Tags
available
drug candidate
Drug indication
Enzyme Inhibitor (aldose reductase)
Diabetic cataract
Drug Status
experimental
investigational
Max Phase
Phase 3
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Chemical structure is derived from . Sorbinil is an experimental aldose reductase inhibitor.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
6
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugMAP
Guide to Pharmacology
MedChem Express Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
30
Molecular Weight
236.06
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
0
Ring Count
3
Aromatic Ring Count
1
cLogP
0.64
TPSA
67.43
Fraction CSP3
0.27
Chiral centers
1.0
Largest ring
6.0
QED
0.65
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
AKR1B1
Aldose Reductase
MOA
Aldose reductase inhibitor
Pathway
Metabolic Enzyme/Protease
Source data
