General
Preferred name
PD007595
Synonyms
??resorcylic acid, p-Hydroxysalicylic acid ()
2,4-DIHYDROXYBENZOIC ACID ()
¦Â-resorcylic acid, p-Hydroxysalicylic acid ()
4-Hydroxysalicylic acid ()
P&D ID
PD007595
CAS
89-86-1
Tags
available
drug candidate
Drug Status
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION 2,4-Dihydroxybenzoic acid is a degradation product of acid cherry anthocyanins during in vitro cell culture and an analogue of coenzyme Q precursor molecules. 2,4-Dihydroxybenzoic acid can improve the related symptoms of kidney diseases caused by ADCK4/Coq6 deficiency[1][2][3].
PRICE 29
DESCRIPTION 4-hydroxysalicylic acid is an inhibitor of the mammalian carbonic anhydrase. (Enamine Bioactive Compounds)
DESCRIPTION 2,4-Dihydroxybenzoic acid is found in alcoholic beverages.2, 4-Dihydroxybenzoic acid is a food flavour ingredient and flavour modifie. (TargetMol Bioactive Compound Library)
Cell lines
1
Organisms
1
Compound Sets
5
DrugBank
DB02839
Enamine Bioactive Compounds
EBC-03238
MedChem Express Bioactive Compound Library
HY-W012575
Selleckchem Bioactive Compound Library
2-4-dihydroxybenzoic-acid
TargetMol Bioactive Compound Library
T5890
External IDs
29
Properties
(calculated by RDKit )
Molecular Weight
154.03
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
3
Rotatable Bonds
1
Ring Count
1
Aromatic Ring Count
1
cLogP
0.8
TPSA
77.76
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.56
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
Human Endogenous Metabolite
Reactive Oxygen Species (ROS)
Reactive Oxygen Species
Pathway
Metabolism
Immunology/Inflammation
Metabolic Enzyme/Protease
NF-κB
NF-¦ÊB
Source data