General
Preferred name
m-Methoxybenzamide
Synonyms
3-MBA ()
3-Methoxybenzamide ()
P&D ID
PD007409
CAS
5813-86-5
6156-13-4
Tags
available
drug candidate
Drug indication
Discovery agent
Drug Status
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION 3-Methoxybenzamide (3-MBA), an inhibitor of ADP-ribosyltransferase (ADPRTs) and PARP, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells[1]. 3-Methoxybenzamide (3-MBA) enhances in vitro plant growth, microtuberization, and transformation efficiency of blue potato (Solanum tuberosum L. subsp. andigenum)[2].
PRICE 29
DESCRIPTION 3-Methoxybenzamide is a competitive inhibitor of poly(ADP-ribose) synthetase with Ki values of less than 2 μM and also inhibits ADP-ribosyltransferase (ADPRT). (BOC Sciences Bioactive Compounds)
DESCRIPTION 3-Methoxybenzamide (3-MBA) is a competitive inhibitor of poly(ADP-ribose) synthetase. (TargetMol Bioactive Compound Library)
Compound Sets
7
BOC Sciences Bioactive Compounds
3-methoxybenzamide-cas-5813-86-5-292103
Cayman Chemical Bioactives
30451
DrugBank
DB03073
DrugMAP
DM245AB
MedChem Express Bioactive Compound Library
HY-121497
Selleckchem Bioactive Compound Library
3-methoxybenzamide
TargetMol Bioactive Compound Library
T7439
External IDs
29
Properties
(calculated by RDKit )
Molecular Weight
151.06
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
1
cLogP
0.79
TPSA
52.32
Fraction CSP3
0.12
Chiral centers
0.0
Largest ring
6.0
QED
0.68
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Bacterial
PARP
poly(ADP-ribose) synthetase
Transferase
Pathway
Chromatin/Epigenetic
DNA Damage/DNA Repair
Metabolism
Microbiology/virology
Anti-infection
Cell Cycle/DNA Damage
Epigenetics
Source data