General
Preferred name
MEVINOLINIC ACID
Synonyms
Mevinolinic acid (sodium) ()
LOVASTATIN ACID ()
Lovastatin hydroxy acid (sodium) ()
Lovastatin Hydroxy Acid (sodium salt) ()
P&D ID
PD007241
CAS
75225-51-3
75225-50-2
Tags
available
drug
Drug indication
Hypercholesterolemia
Drug Status
approved
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
2
Compound Sets
7
Cayman Chemical Bioactives
ChEMBL Drugs
DrugBank
DrugMAP
DrugMAP Approved Drugs
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
39
Properties
(calculated by RDKit )
Molecular Weight
422.27
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
3
Rotatable Bonds
10
Ring Count
2
Aromatic Ring Count
0
cLogP
3.72
TPSA
104.06
Fraction CSP3
0.75
Chiral centers
8.0
Largest ring
6.0
QED
0.46
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolic Enzyme/Protease
Target
HMG-CoA Reductase (HMGCR)
Source data
