General
Preferred name
TYROSINE
Synonyms
(S)-Tyrosine ()
P-Tyrosine ()
L-p-Tyrosine ()
L-Tyrosine(S)-Tyrosine ()
Tyrosine ()
L-tyrosine ()
NSC-82624 ()
Levodopa impurity, l-tyrosine- ()
FEMA NO. 3736 ()
Levodopa related compound l-tyrosine ()
L-Tyrosine-13C9,15N ()
L-Tyrosine (sodium salt hydrate) ()
P&D ID
PD007194
CAS
202407-26-9
25619-78-7
140-43-2
1189756-47-5
60-18-4
122666-87-9
Tags
natural product
drug
available
Approved by
FDA
Drug Status
nutraceutical
investigational
approved
withdrawn
Drug indication
Malnutrition
Amino Acid
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Tyrosine is precursor to noradenaline. (GtoPdb)
Compound Sets
21
Cayman Chemical Bioactives
31256
36333
ChEMBL Approved Drugs
CHEMBL925
ChEMBL Drugs
CHEMBL925
Concise Guide to Pharmacology 2017/18
4791
Concise Guide to Pharmacology 2019/20
4791
Concise Guide to Pharmacology 2021/22
4791
Concise Guide to Pharmacology 2023/24
4791
Drug Repurposing Hub
DrugBank
DB00135
DrugBank Approved Drugs
DB00135
DrugCentral
2786
DrugCentral Approved Drugs
2786
DrugMAP
DM9O8DT
DrugMAP Approved Drugs
DM9O8DT
Enamine BioReference Compounds
Guide to Pharmacology
4791
Mcule NIBR MoA Box Subset
MCULE-8059108702
MedChem Express Bioactive Compound Library
HY-N0473
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
Withdrawn 2.0
1329
External IDs
61
Properties
(calculated by RDKit )
Molecular Weight
181.07
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
3
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
1
cLogP
0.35
TPSA
83.55
Fraction CSP3
0.22
Chiral centers
1.0
Largest ring
6.0
QED
0.63
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
Amino Acids and Derivatives inhibitor
Tyrosine hydroxylase inhibitor
Target
Amino Acids and Derivatives
TAT, TH, YARS, YARS2
Endogenous Metabolite
Member status
member
ATC
N
Therapeutic Class
Dietary supplement
Pathway
Metabolic Enzyme/Protease
Source data