General
Preferred name
PF-00356231
Synonyms
PF 00356231 ()
PF-00356231 (hydrochloride) ()
P&D ID
PD007047
CAS
766536-21-4
820223-77-6
Tags
available
drug candidate
Drug indication
Discovery agent
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
PF 00356231 is a MMP-12 inhibitor, and at high concentrations it also inhibits other MMPs.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
6
Axon Medchem Screening Library
BOC Sciences Bioactive Compounds
DrugBank
DrugMAP
MedChem Express Bioactive Compound Library
ZINC Tool Compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
23
Molecular Weight
428.12
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
7
Ring Count
4
Aromatic Ring Count
4
cLogP
5.42
TPSA
79.29
Fraction CSP3
0.08
Chiral centers
1.0
Largest ring
6.0
QED
0.41
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
MMP inhibitor
MMP
Pathway
Metabolic Enzyme/Protease
Source data
