General
Preferred name
I-CBP 112
Synonyms
P&D ID
PD007013
CAS
1640282-31-0
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
I-CBP112 has been found to be a CBP/p300 bromodomain inhibitor and could reduce the leukemia-initiating potential of MLL-AF9(+) acute myeloid leukemia cells.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
1
BOC Sciences Bioactive Compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
6
Molecular Weight
468.26
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
0
Rotatable Bonds
7
Ring Count
4
Aromatic Ring Count
2
cLogP
4.22
TPSA
60.47
Fraction CSP3
0.52
Chiral centers
1.0
Largest ring
7.0
QED
0.61
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
