General
Preferred name
BROPIRIMINE
Synonyms
U-54461 ()
U-54,461 ()
NSC-149027 ()
P&D ID
PD006914
CAS
56741-95-8
Tags
available
drug
Drug indication
Virus infection
Antineoplastic
Antiviral
Drug Status
experimental
approved
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION HIF-1alpha inhibitor; down-regulates HIF-1alpha protein synthesis (Tocris Bioactive Compound Library)
Compound Sets
16
Cayman Chemical Bioactives
29440
ChEMBL Drugs
CHEMBL37387
Drug Repurposing Hub
DrugBank
DB04168
DrugCentral
3689
DrugCentral Approved Drugs
3689
DrugMAP
DMMT1YQ
DrugMatrix
Enamine BioReference Compounds
EU-OPENSCREEN Bioactive Compound Library
EOS101973
MedChem Express Bioactive Compound Library
HY-W008634
NPC Screening Collection
Pandemic Response Box
ReFrame library
TargetMol Bioactive Compound Library
T5521
Tocris Bioactive Compound Library
4316
External IDs
29
Properties
(calculated by RDKit )
Molecular Weight
264.99
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
1
Ring Count
2
Aromatic Ring Count
2
cLogP
1.78
TPSA
71.77
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.83
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Primary Target
Cytokines
MOA
interferon inducer
Pathway
Immunology/Inflammation
Target
Toll-like Receptor (TLR)
Source data