General
Preferred name
MATAIRESINOL
Synonyms
P&D ID
PD006886
CAS
580-72-3
Tags
drug candidate
available
Drug Status
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Matairesinol confers anti-allergic effects in an allergic dermatitis mouse model. DfE-induced changes in IL-4 and IFN-¦Ã mRNA expression in the ears of NC/Nga mice were reversed by matairesinol application[1].
PRICE 208
DESCRIPTION Matairesinol is a phytolignan found in a variety of foods such as seeds, vegetables and fruits.Matairesinol has a variety of biological functions including anti-angiogenic, anti-cancer and anti-fungal activities; the anti-osteoporotic activity of matairesinol may derive from its anti-osteoclastic potential through p38/ERK-NFATc1 signaling , rather than through an anti-resorptive effect.
Cell lines
7
Organisms
2
Compound Sets
3
Cayman Chemical Bioactives
10005174
DrugBank
DB04200
MedChem Express Bioactive Compound Library
HY-N3312
External IDs
30
Properties
(calculated by RDKit )
Molecular Weight
358.14
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
6
Ring Count
3
Aromatic Ring Count
2
cLogP
2.69
TPSA
85.22
Fraction CSP3
0.35
Chiral centers
2.0
Largest ring
6.0
QED
0.77
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
Pathway
Metabolic Enzyme/Protease
Source data