General
Preferred name
Capric acid
Synonyms
DECANOIC ACID ()
Sodium caprate ()
Decoic acid ()
Caprynic acid ()
DA, Decanoic acid, Decylic acid ()
Decanoic Acid-d3 ()
Decanoic Acid-d19 ()
Decanoic Acid-d2 ()
P&D ID
PD006780
CAS
334-48-5
52627-73-3
102611-15-4
88170-22-3
62716-49-8
Tags
available
drug candidate
Drug indication
Discovery agent
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Decanoic acid is a key component of the medium-chain triglyceride (MCT) found in coconut oil. Decanoic acid is a brain-penetrant and non-competitive inhibitor of AMPA receptor showing antiseizure activity in rats. Decanoic acid reduces tyrosinase activity and inhibits melanosome maturation. Decanoic acid suppresses the phosphorylation of c-Met and induced apoptosis in hepatocellular carcinoma (HCC) cells by inhibiting the expression of various oncogenic proteins, which is promising for research in the field of mTORC1 signaling, HCC and epilepsy[1][2][3].
PRICE
29
DESCRIPTION
Decanoic acid is a medium-chain saturated fatty acid. It is a non-competitive antagonist at AMPA receptors.
(Enamine Bioactive Compounds)
DESCRIPTION
Decanoic Acid (Caprynic acid) acts as a non-competitive AMPA receptor antagonist.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
15
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugBank
DrugMAP
Enamine Bioactive Compounds
Guide to Pharmacology
MedChem Express Bioactive Compound Library
NPC Screening Collection
NURSA ligand set
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
60
Molecular Weight
172.15
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
8
Ring Count
0
Aromatic Ring Count
0
cLogP
3.21
TPSA
37.3
Fraction CSP3
0.9
Chiral centers
0.0
Largest ring
0.0
QED
0.57
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Membrane Transporter/Ion Channel
Neuroscience
Metabolic Enzyme/Protease
Neuronal Signaling
Protein Tyrosine Kinase/RTK
Target
c-Met/HGFR
Endogenous Metabolite
Glutaminase
iGluR
Tyrosinase
GluR,PPAR
AMPA
Source data
