General
Preferred name
PD006740
Synonyms
3-HYDROXY-2-AMINOBENZOIC ACID ()
3-Hydroxyanthranilic Acid ()
3-hydroxy Anthranilic Acid ()
P&D ID
PD006740
CAS
548-93-6
4920-81-4
Tags
available
drug candidate
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
3-Hydroxyanthranilic acid is a tryptophan metabolite in the kynurenine pathway.3-hydroxyanthranilic acid has anti-inflammatory, neuroprotective, and lipid-lowering effects. 3-hydroxyanthranilic acid can be used for researches of cardiovascular diseases, tumors, and metabolic diseases[1][2][3][4][5][6][7][8].
PRICE
29
DESCRIPTION
3-Hydroxyanthranilic acid inhibits 3-hydroxyanthranilate 3,4-dioxygenase.
(Enamine Bioactive Compounds)
DESCRIPTION
3-Hydroxy anthranilic acid is an intermediate in the oxidative metabolism of tryptophan in the kynurenine pathway that demonstrates immunoprotective effects.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
3-Hydroxyanthranilic acid is a tryptophan metabolite in the kynurenine pathway. It has been found in human epidermis and bladder tissue and has been detected in a variety of biological fluids such as urine and blood. Within cells, it is primarily located in the cytoplasm. It is present in all eukaryotes from yeast to humans. 3-Hydroxyanthranilic acid has antioxidant activity.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
8
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
DrugBank
Enamine Bioactive Compounds
Mcule NIBR MoA Box Subset
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
32
Molecular Weight
153.04
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
3
Rotatable Bonds
1
Ring Count
1
Aromatic Ring Count
1
cLogP
0.67
TPSA
83.55
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.41
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
antioxidant
Endogenous Metabolite
Member status
member
MOA
aldehyde dehydrogenase inhibitor
Pathway
Metabolism
oxidation-reduction
Metabolic Enzyme/Protease
Source data
