General
Preferred name
PD006716
Synonyms
TCS 401 ()
2-(Oxalyl-Amino)-4,5,6,7-Tetrahydro-Thieno[2,3-C]Pyridine-3-Carboxylic Acid ()
P&D ID
PD006716
CAS
243966-09-8
Tags
available
drug candidate
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
25
DESCRIPTION
TCS 401 is a selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B) with a Ki value of 0.29 ??M.
DESCRIPTION
Mitochondrial pyruvate dehydrogenase kinase (PDK) inhibitor
(Tocris Bioactive Compound Library)
DESCRIPTION
TCS 401 is a selective inhibitor of protein-tyrosine phosphatase 1B (PTP1B) with a Ki value of 0.29 μM.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
7
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
26
Molecular Weight
270.03
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
4
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
1
cLogP
0.12
TPSA
115.73
Fraction CSP3
0.3
Chiral centers
0.0
Largest ring
6.0
QED
0.57
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
phosphatase
PTP1B
Primary Target
Protein Tyrosine Phosphatases
MOA
Inhibitor
Pathway
Metabolic Enzyme/Protease
Metabolism
Source data
