General
Preferred name
Phloretic acid
Synonyms
Phloretate ()
3-(4-Hydroxyphenyl)propanoic acid ()
Hydro-p-coumaric acid ()
3-(4-Hydroxyphenyl)propionic acid ()
Desaminotyrosine ()
Desaminotyrosine, Hydro-p-coumaric acid, Phloretate, 3-(4-Hydroxyphenyl)propanoic acid ()
HYDROXYPHENYL PROPIONIC ACID ()
4-Hydroxyhydrocinnamic acid ()
P&D ID
PD006673
CAS
501-97-3
Tags
available
drug candidate
Drug Status
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Desaminotyrosine is a microbially associated metabolite protecting from influenza through augmentation of type I interferon signaling.
PRICE 29
DESCRIPTION 4-Hydroxyhydrocinnamic acid is a potential antioxidant. It has inhibitory activity against histone deacetylase 6, tyrosine-protein kinase ITK/TSK. (Enamine Bioactive Compounds)
DESCRIPTION Desaminotyrosine (3-(4-Hydroxyphenyl)propionic acid) is a microbially associated metabolite. Desaminotyrosine protects from influenza through augmentation of type I interferon signaling. (TargetMol Bioactive Compound Library)
Cell lines
0
Organisms
1
Compound Sets
5
DrugBank
DB03897
Enamine Bioactive Compounds
EBC-47188
MedChem Express Bioactive Compound Library
HY-W015346
Selleckchem Bioactive Compound Library
phloretic-acid
TargetMol Bioactive Compound Library
T2862
External IDs
50
Properties
(calculated by RDKit )
Molecular Weight
166.06
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
1
cLogP
1.41
TPSA
57.53
Fraction CSP3
0.22
Chiral centers
0.0
Largest ring
6.0
QED
0.71
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
Influenza Virus
Pathway
Metabolism
Microbiology/virology
Anti-infection
Metabolic Enzyme/Protease
Source data