General
Preferred name
NEAMINE
Synonyms
Neamine (tetrahydrochloride) ()
Neamine tetrahydrochloride ()
Neamine (hydrochloride) ()
P&D ID
PD006374
CAS
1404-04-2
3947-65-7
15446-43-2
Tags
available
drug candidate
Drug indication
Discovery agent
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Neamine tetrahydrochloride, a degradation product of Neomycin, is a broad-spectrum aminoglycoside antibiotic. Neamine tetrahydrochloride is an anti-angiogenesis agent targeting angiogenin. Neamine tetrahydrochloride has potent antibacterial, antitumor and neuroprotective activities[1][2].
PRICE
57
DESCRIPTION
Neamine tetrahydrochloride is a broad-spectrum aminoglycoside antibiotic with antibacterial, antitumor and neuroprotective activities, inhibits the growth of pancreatic cancer cells, and inhibits the proliferation of oral cancer cells. Neamine tetrahydrochloride inhibits xenogeneic human tumor growth and angiogenesis in athymic mice and can be used to study oral and pancreatic cancer.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
6
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
39
Molecular Weight
322.19
Hydrogen Bond Acceptors
10
Hydrogen Bond Donors
8
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
0
cLogP
-5.12
TPSA
203.46
Fraction CSP3
1.0
Chiral centers
10.0
Largest ring
6.0
QED
0.25
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
antibiotic
Bacterial
Antibacterial
Pathway
Microbiology/virology
Anti-infection
Source data
