General
Preferred name
Lumichrome
Synonyms
7,8-Dimethylalloxazine ()
P&D ID
PD006289
CAS
1086-80-2
Tags
available
drug candidate
Drug Status
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
DESCRIPTION Lumichrome is an endogenous compound in humans, produced by photodegradation of riboflavin. It utilizes a p53-dependent mechanism to inhibit growth and induce apoptosis in human lung cancer cells. (TargetMol Bioactive Compound Library)
Compound Sets
5
Cayman Chemical Bioactives
20730
DrugBank
DB04345
MedChem Express Bioactive Compound Library
HY-115385
Selleckchem Bioactive Compound Library
lumichrome
TargetMol Bioactive Compound Library
T5061
External IDs
35
Properties
(calculated by RDKit )
Molecular Weight
242.08
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
0
Ring Count
3
Aromatic Ring Count
1
cLogP
0.73
TPSA
91.5
Fraction CSP3
0.17
Chiral centers
0.0
Largest ring
6.0
QED
0.57
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Akt
Apoptosis
ERK
MDM-2/p53
NF-κB
Nuclear Factor of activated T Cells (NFAT)
p38 MAPK
β-catenin
Endogenous Metabolite
Pathway
Immunology/Inflammation
MAPK/ERK Pathway
PI3K/Akt/mTOR
Stem Cell/Wnt
Metabolism
Source data