General
Preferred name
ISOFERULIC ACID
Synonyms
Isoferulate ()
Hesperetic acid ()
3-Hydroxy-4-methoxycinnamic acid ()
Hesperetate ()
trans-Isoferulic acid ()
trans-3-Hydroxy-4-methoxycinnamic acid ()
Hesperetic acid, Hesperetate, Isoferulate ()
P&D ID
PD006097
CAS
537-73-5
25522-33-2
Tags
available
drug candidate
Drug indication
Discovery agent
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Isoferulic acid (3-Hydroxy-4-methoxycinnamic acid) is an orally active cinnamic acid derivative. Isoferulic acid exhibits hypoglycemic, antiviral, and antioxidant activities. Isoferulic acid can also inhibit fructose- and glucose-mediated protein glycation. Isoferulic acid can be used in the research of diseases such as diabetes[1][2][3][4].
DESCRIPTION
trans-Isoferulic acid (trans-3-Hydroxy-4-methoxycinnamic acid) is an aromatic acid isolated from the roots of Clematis florida var. plena. trans-Isoferulic acid exhibits anti-inflammatory activity[1].trans-isoferulic acid suppresses NO and PGE2 production through the induction of Nrf2-dependent heme oxygenase-1 (HO-1)[2].
PRICE
29
DESCRIPTION
trans-Isoferulic acid is an aromatic acid isolated from the roots of Clematis florida var. plena. trans-Isoferulic acid exhibits anti-inflammatory activity. It has binding affinity against α1A-adrenoceptors.
(Enamine Bioactive Compounds)
DESCRIPTION
Isoferulic acid (Hesperetate) exhibits hypoglycemic properties.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
7
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
33
Molecular Weight
194.06
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
1
cLogP
1.5
TPSA
66.76
Fraction CSP3
0.1
Chiral centers
0.0
Largest ring
6.0
QED
0.72
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Adrenergic Receptor
Influenza Virus
NO Synthase
Prostaglandin Receptor
Pathway
GPCR/G protein
Microbiology/virology
Neuroscience
Anti-infection
Neuronal Signaling
Immunology/Inflammation
Source data
