General
Preferred name
GLUCONOLACTONE
Synonyms
Gluconic acid lactone ()
Delta-Gluconolactone ()
D-(+)-Glucono-1,5-lactone ()
D-gluconic acid delta-lactone ()
NSC-34393 ()
INS-575 ()
Glucono-delta-lactone ()
E-575 ()
Riken lactone ()
Glucono .delta. lactone ()
.delta.-d-gluconolactone ()
Gluconolactone component of renacidin ()
Glucono .delta.-lactone ()
Glucono delta-lactone ()
NSC-758238 ()
E575 ()
INS NO.575 ()
D-glucono-1,5-lactone ()
D-gluconic acid .delta.-lactone ()
Fujiglucon ()
Lysactone ()
P&D ID
PD006000
CAS
4253-68-3
1335-57-5
90-80-2
Tags
available
drug
Approved by
FDA
First approval
1990
Drug indication
Discovery agent
Drug Status
approved
experimental
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
D-(+)-Glucono-1,5-lactone is a polyhydroxy (PHA) that is capable of metal chelating, moisturizing and antioxidant activity.
PRICE
29
DESCRIPTION
Gluconolactone is a polyhydroxy acid used in the dissolution of calculi and used as an additive in various drug products to maintain consistency and other characteristics.
(Enamine Bioactive Compounds)
DESCRIPTION
D-(+)-Glucono-1,5-lactone (Gluconolactone) is a naturally occurring food additive used as a sequestrant, acidifier, curing agent, pickling agent, or leavening agent. It is a cyclic ester of D-gluconic acid and appears as a white, odorless crystalline powder.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
12
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
Enamine Bioactive Compounds
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
NPC Screening Collection
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
64
Molecular Weight
178.05
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
4
Rotatable Bonds
1
Ring Count
1
Aromatic Ring Count
0
cLogP
-3.01
TPSA
107.22
Fraction CSP3
0.83
Chiral centers
4.0
Largest ring
6.0
QED
0.32
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
NF-¦ÊB
Immunology/Inflammation
Metabolism
NF-κB
Metabolic Enzyme/Protease
Target
Endogenous Metabolite
LPH
Reactive Oxygen Species
Reactive Oxygen Species (ROS)
Source data
