General
Preferred name
APRAMYCIN
Synonyms
Nebramycin II ()
Ai3-29795 ()
Apramycin (sulfate) ()
Nebramycin II (sulfate) ()
APRAMYCIN SULFATE ()
Apramycin (sulfate hyrate) ()
P&D ID
PD005954
CAS
37321-09-8
65710-07-8
Tags
available
drug
natural product
Approved by
FDA
Drug indication
Gram-negative bacterial infection
Drug Status
vet_approved
approved
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
Apramycin is an aminoglycoside antibacterial compound that was originally isolated from Streptomyces tenebrarius. The compound has activity against Gram-negative bacteria .
(GtoPdb)
DESCRIPTION
Apramycin sulfate (Nebramycin II) is an aminoglycoside antibiotic.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
12
Cayman Chemical Bioactives
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugMAP
Guide to Pharmacology
MedChem Express Bioactive Compound Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
38
Molecular Weight
539.28
Hydrogen Bond Acceptors
16
Hydrogen Bond Donors
11
Rotatable Bonds
6
Ring Count
4
Aromatic Ring Count
0
cLogP
-6.95
TPSA
283.64
Fraction CSP3
1.0
Chiral centers
17.0
Largest ring
6.0
QED
0.15
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Bacterial
16S rRNA
antibiotic
Antibiotics
Pathway
Anti-infection
Microbiology/virology
MOA
Antibacterial inhibitor
bacterial 30S ribosomal subunit inhibitor
Indication
gram-negative bacterial infections
Source data
