General
Preferred name
ALDOSTERONE
Synonyms
CHEMBL273453 ()
[3H]aldosterone ()
NSC-73856 ()
P&D ID
PD005950
CAS
52-39-1
10328-70-8
Tags
available
probe
natural product
drug
Drug indication
Hypertension
Drug Status
experimental
investigational
approved
Max Phase
Phase 1
Probe info
Probe selectivity
protein-selective
Probe type
P&D approved
calculated probe
Probe sources
High-quality chemical probes
Tool Compound Set
Probe targets
[[ compound.targets[t].gene_name ]]
Probe control
Probe control not defined
Orthogonal probes
1
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
18
Cayman Chemical Bioactives
ChEMBL Drugs
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
High-quality chemical probes
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
NURSA ligand set
Tool Compound Set
ZINC Tool Compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
42
Properties
(calculated by RDKit )
Molecular Weight
360.19
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
0
cLogP
1.85
TPSA
91.67
Fraction CSP3
0.76
Chiral centers
7.0
Largest ring
6.0
QED
0.75
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Mineralocorticoid Receptor
Endogenous Metabolite
Therapeutic Class
Antihypertensive Agents
Pathway
Metabolic Enzyme/Protease
Source data
