General
Preferred name
c-Fms-IN-2
Synonyms
5-CYANO-FURAN-2-CARBOXYLIC ACID [5-HYDROXYMETHYL-2-(4-METHYL-PIPERIDIN-1-YL)-PHENYL]-AMIDE ()
P&D ID
PD005666
CAS
791587-67-2
Tags
drug candidate
available
Drug Status
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION c-Fms-IN-2 is a FMS kinase inhibitor with an IC50 of 0.024 ¦ÌM.
PRICE 313
DESCRIPTION c-Fms-IN-2 is an inhibitor of c-FMS kinase (IC50 = 24 nM). (TargetMol Bioactive Compound Library)
Compound Sets
3
DrugBank
DB07167
MedChem Express Bioactive Compound Library
HY-18787
TargetMol Bioactive Compound Library
T10775
External IDs
15
Properties
(calculated by RDKit )
Molecular Weight
339.16
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
3
Aromatic Ring Count
2
cLogP
3.13
TPSA
89.5
Fraction CSP3
0.37
Chiral centers
0.0
Largest ring
6.0
QED
0.89
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
c-Fms
Pathway
Protein Tyrosine Kinase/RTK
Tyrosine Kinase/Adaptors
Source data