General
Preferred name
BMS-564929
Synonyms
BMS 564929 ()
PS178990 ()
P&D ID
PD005382
CAS
627530-84-1
Tags
available
drug candidate
Drug indication
Discovery agent
Drug Status
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION BMS-564929 is an androgen receptor (AR) agonist, binds to androgen receptor (AR) with a Ki of 2.11¡À0.16 nM.
PRICE 1980
DESCRIPTION BMS-564929 is a highly effective androgen receptor (AR) agonist that upregulates the expression and activity of lipogenic enzymes, reduces VAT content and lipid content, and downregulates the expression of acetyl-CoA carboxylase, FASN, and SCD.
DESCRIPTION Potent and selective PPARgamma agonist; antidiabetic agent (Tocris Bioactive Compound Library)
Compound Sets
8
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
DrugBank
DB07286
DrugMAP
DMILMHZ
JUMP-MOA Compound Set
9882972
MedChem Express Bioactive Compound Library
HY-12111
ReFrame library
Tocris Bioactive Compound Library
5274
External IDs
20
Properties
(calculated by RDKit )
Molecular Weight
305.06
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
1
Ring Count
3
Aromatic Ring Count
1
cLogP
1.42
TPSA
84.64
Fraction CSP3
0.36
Chiral centers
2.0
Largest ring
6.0
QED
0.8
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Androgen Receptor
AR
Primary Target
Androgen Receptors
MOA
Agonist
Androgen Receptor modulator
Pathway
Vitamin D Related/Nuclear Receptor
Source data