General
Preferred name
ACIFLUORFEN
Synonyms
P&D ID
PD005331
CAS
50594-66-6
Tags
available
drug candidate
Drug Status
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
DESCRIPTION Acifluorfen, a protoporphyrinogen oxidase (PROTOX) inhibitor herbicide, promotes the accumulation of protoporphyrin IX (PPIX), and induces tumors in the rodent liver. Acifluorfen causes strong photooxidative destruction of pigments and lipids in sensitive plant species[1][2].
DESCRIPTION Acifluorfen, a protoporphyrinogen oxidase (PROTOX) inhibitor herbicide, promotes the accumulation of protoporphyrin IX (PPIX) and induces tumors in rodent livers, causing significant photooxidative damage to pigments and lipids in sensitive plant species. (TargetMol Bioactive Compound Library)
Cell lines
0
Organisms
1
Compound Sets
6
DrugBank
DB07338
EU-OPENSCREEN Bioactive Compound Library
EOS102360
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL222440
MedChem Express Bioactive Compound Library
HY-128075
TargetMol Bioactive Compound Library
T40588
ZINC Tool Compounds
ZINC000002032367
External IDs
26
Properties
(calculated by RDKit )
Molecular Weight
361.0
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
2
Aromatic Ring Count
2
cLogP
4.76
TPSA
89.67
Fraction CSP3
0.07
Chiral centers
0.0
Largest ring
6.0
QED
0.63
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
Herbicide
Pathway
Metabolic Enzyme/Protease
Source data