General
Preferred name
AZOXYSTROBIN
Synonyms
HSDB 7017 ()
ICI-A 5504 ()
Bankit ()
ICIA-5504 ()
Amistar ()
P&D ID
PD005287
CAS
131860-33-8
Tags
available
drug candidate
Drug Status
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE 29
DESCRIPTION Azoxystrobin is an orally active, broad-spectrum ¦Â-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis[1][2][3][4].
DESCRIPTION Azoxystrobin (Bankit) is a broad-spectrum fungicide. Azoxystrobin induces ROS production, cell apoptosis and mitochondrial respiration by blocking electron transfer between cytochromes b and c1. (TargetMol Bioactive Compound Library)
Cell lines
1
Organisms
2
Compound Sets
5
Cayman Chemical Bioactives
24056
DrugBank
DB07401
MedChem Express Bioactive Compound Library
HY-B0849
TargetMol Bioactive Compound Library
T21275
The Pathogen Box
External IDs
25
Properties
(calculated by RDKit )
Molecular Weight
403.12
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
0
Rotatable Bonds
7
Ring Count
3
Aromatic Ring Count
3
cLogP
4.09
TPSA
103.56
Fraction CSP3
0.09
Chiral centers
0.0
Largest ring
6.0
QED
0.33
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Disease
MALARIA
Pathway
Metabolism
Microbiology/virology
Anti-infection
Immunology/Inflammation
Metabolic Enzyme/Protease
NF-κB
NF-¦ÊB
Target
Apoptosis
Bacterial
Fungal
phosphatase
Reactive Oxygen Species (ROS)
Reactive Oxygen Species
Antifungal
Source data