General
Preferred name
FARNESYL DIPHOSPHATE
Synonyms
SQ-32709 ()
Farnesyl Pyrophosphate (ammonium) ()
Farnesyl diphosphate (ammonium) ()
Farnesyl Pyrophosphate ammonium salt ()
Farnesyl Pyrophosphate (ammonium salt) ()
trans,trans-farnesyl diphosphate ()
(E,E)-Farnesyl Pyrophosphate ammonium salt ()
(ZE)-Farnesyl Pyrophosphate ammonium salt ()
P&D ID
PD005040
CAS
372-97-4
116057-57-9
1053215-81-8
Tags
available
drug candidate
Drug indication
Arteriosclerosis
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
476
DESCRIPTION
Farnesyl Pyrophosphate ammonium (Farnesyl diphosphate ammonium) is a metabolic intermediate of the MVA pathway that acts as a newly identified danger signal to trigger acute cell death and induce neuronal loss in stroke.
PRICE
592
DESCRIPTION
(ZE)-Farnesyl Pyrophosphate ammonium salt is an isomer of (E,E)-Farnesyl Pyrophosphate ammonium salt, which is a key metabolic intermediate in the mevalonate (MVA) pathway and an agonist of TRPM2, and is involved in cholesterol synthesis, ubiquinone synthesis, protein farnesylation and other physiological processes.
DESCRIPTION
Farnesyl pyrophosphate is an intermediate in the HMG-CoA reductase pathway and also acts as a donor in post-translational isoprenylation of proteins. It has been identified as an antagonist of P2Y12 receptors.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
11
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugBank
DrugMAP
Guide to Pharmacology
MedChem Express Bioactive Compound Library
Other bioactive compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
57
Molecular Weight
382.13
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
3
Rotatable Bonds
11
Ring Count
0
Aromatic Ring Count
0
cLogP
4.63
TPSA
113.29
Fraction CSP3
0.6
Chiral centers
1.0
Largest ring
0.0
QED
0.35
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
TRP Channel
Pathway
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
Source data
