General
Preferred name
FARNESYL DIPHOSPHATE
Synonyms
SQ-32709 ()
Farnesyl Pyrophosphate ammonium salt ()
trans,trans-farnesyl diphosphate ()
Farnesyl Pyrophosphate (ammonium salt) ()
P&D ID
PD005040
CAS
372-97-4
116057-57-9
Tags
drug candidate
natural product
available
Drug indication
Arteriosclerosis
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Farnesyl pyrophosphate is an intermediate in the HMG-CoA reductase pathway and also acts as a donor in post-translational isoprenylation of proteins. It has been identified as an antagonist of P2Y12 receptors.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
9
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugBank
DrugMAP
Guide to Pharmacology
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
49
Molecular Weight
382.13
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
3
Rotatable Bonds
11
Ring Count
0
Aromatic Ring Count
0
cLogP
4.63
TPSA
113.29
Fraction CSP3
0.6
Chiral centers
1.0
Largest ring
0.0
QED
0.35
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
