General
Preferred name
LATRUNCULIN B
Synonyms
NSC-339663 ()
P&D ID
PD004807
CAS
76343-94-7
Tags
drug candidate
natural product
available
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Latrunculin B is a marine toxin which acts as an inhibitor of actin polymerization. It causes concentration-dependent changes in cell shape and actin organization.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
4
Organisms
0
Compound Sets
5
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
Drug Repurposing Hub
DrugBank
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
19
Molecular Weight
395.18
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
1
Ring Count
3
Aromatic Ring Count
0
cLogP
3.3
TPSA
84.86
Fraction CSP3
0.7
Chiral centers
5.0
Largest ring
14.0
QED
0.52
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
ACTA1, MKL1, SPIRE2
MOA
actin polymerization inhibitor
Source data
