General
Preferred name
tetraethylammonium
Synonyms
Tetrylammonium bromide ()
TETRAETHYLAMMONIUM CHLORIDE ()
TETRAETHYLAMMONIUM HYDROXIDE ()
TEAB ()
TEA bromide ()
[14C]TEA ()
Tetraethylammonium (chloride) ()
TEAB, TEA bromide ()
TEA chloride ()
Tetraethylammonium bromide ()
TETRYLAMMONIUM ()
Tetraethylammonium ion ()
NSC-156315 ()
NSC-102778 ()
Tetraethylammonium cation ()
Tetramon ()
Sympatektoman ()
Beparon ()
Ethylon ()
Tetranium ()
Etamon ()
Bromuro de tetrilamonio ()
Etambro ()
Etylon ()
NSC-36724 ()
Teamon ()
Bromure de tetrylammonium ()
Tmd-10 ()
Bromethyl ()
P&D ID
PD004524
CAS
56-34-8
66-40-0
588683-10-7
77-98-5
71-91-0
65129-07-9
1941-26-0
Tags
available
drug candidate
Drug indication
Discovery agent
Drug Status
experimental
investigational
Max Phase
2.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
MOA Tetraethylammonium's mechanism of action is still being investigated, but it is known that it blocks autonomic ganglia, calcium- and voltage- activated potassium channels, and nicotinic acetylcholine receptors.;
DESCRIPTION Tetraethylammonium chloride is a non-selective potassium channel blocker. Tetraethylammonium chloride is a good substrate for organic cation transporter (OCTN1). Tetraethylammonium chloride antitumor properties[1][2].
PRICE 29
PRICE 1300
DESCRIPTION Benzodiazepine inverse agonist (Tocris Bioactive Compound Library)
DESCRIPTION Nicotinic acetylcholine receptor antagonist; K+ channel blocker (LOPAC library)
DESCRIPTION Tetraethylammonium chloride is a non-selective potassium channel blocker. (Enamine Bioactive Compounds)
DESCRIPTION Tetraethylammonium chloride is a quaternary ammonium compound. It is a non-selective potassium channel blocker. It is a good substrate for organic cation transporter proteins and has antitumor properties. (TargetMol Bioactive Compound Library)
DESCRIPTION Tetraethylammonium bromide is a selective potassium channel blocker. (BOC Sciences Bioactive Compounds)
DESCRIPTION Tetraethylammonium bromide (TEA bromide) can selectively block potassium channels. (TargetMol Bioactive Compound Library)
Cell lines
1
Organisms
1
Compound Sets
20
BOC Sciences Bioactive Compounds
tetraethylammoniumbromide-n-cas-71-91-0-item-151902
ChEMBL Drugs
CHEMBL9324
CHEMBL434435
CHEMBL324254
Concise Guide to Pharmacology 2017/18
2343
4575
Concise Guide to Pharmacology 2019/20
2343
4575
Concise Guide to Pharmacology 2021/22
2343
4575
Concise Guide to Pharmacology 2023/24
2343
4575
DrugBank
DB08837
DrugMAP
DM6SFYH
DrugMatrix
Enamine Bioactive Compounds
EBC-151154
Guide to Pharmacology
2343
4575
Ki Database
TETRAETHYLAMMONIUM
LOPAC library
MedChem Express Bioactive Compound Library
HY-B1793
NPC Screening Collection
Other bioactive compounds
Selleckchem Bioactive Compound Library
tetraethylammonium-chloride
tetraethylammonium-bromide
TargetMol Bioactive Compound Library
T7538
T8361
Tocris Bioactive Compound Library
3068
ZINC Tool Compounds
ZINC000000896981
External IDs
86
Properties
(calculated by RDKit )
Molecular Weight
130.16
Hydrogen Bond Acceptors
0
Hydrogen Bond Donors
0
Rotatable Bonds
4
Ring Count
0
Aromatic Ring Count
0
cLogP
1.88
TPSA
0.0
Fraction CSP3
1.0
Chiral centers
0.0
Largest ring
0.0
QED
0.51
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
Nicotinic
Target
Potassium Channel
Primary Target
Voltage-gated Potassium (KV) Channels
MOA
Blocker
Pathway
Membrane Transporter/Ion Channel
Source data