General
Preferred name
DIHYDRORESVERATROL
Synonyms
3,4',5-Trihydroxybibenzyl ()
5-[2-(4-hydroxyphenyl)ethyl]benzene-1,3-diol ()
P&D ID
PD004373
CAS
58436-28-5
Tags
available
drug candidate
nuisance
Drug indication
Discovery agent
Drug Status
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Dihydroresveratrol, a potent phytoestrogen, is a hormone receptor modulator. Dihydroresveratrol exhibits proliferative effects in androgen-independent prostate and breast cancer cells at picomolar and nanomolar concentrations[1].
PRICE 49
DESCRIPTION Dihydroresveratrol (3,4',5-Trihydroxybibenzyl) is a major metabolite of resveratrol that is produced by animal-associated bacteria, including the gut microbiota. Dihydroresveratrol and dihydroresveratrol monosulfate are detectable in urine. The physiological effects of dihydroresveratrol have not been investigated. (TargetMol Bioactive Compound Library)
Cell lines
1
Organisms
1
Compound Sets
7
Cayman Chemical Bioactives
19651
DrugBank
DB08466
DrugMAP
DM1KO7U
MedChem Express Bioactive Compound Library
HY-N3755
Nuisance compounds in cellular assays
Selleckchem Bioactive Compound Library
dihydroresveratrol
TargetMol Bioactive Compound Library
T3840
External IDs
25
Properties
(calculated by RDKit )
Molecular Weight
230.09
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
3
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
2
cLogP
2.59
TPSA
60.69
Fraction CSP3
0.14
Chiral centers
0.0
Largest ring
6.0
QED
0.76
Structural alerts
1
Nonspecific/NOS
Resveratrols
Nuisance compounds
Custom attributes
(extracted from source data)
Target
Estrogen Receptor/ERR
Estrogen/progestogen Receptor
Pathway
Vitamin D Related/Nuclear Receptor
Endocrinology/Hormones
Source data