General
Preferred name
TRIMAZOSIN
Synonyms
Trimazosin HCl ()
TRIMAZOSIN HYDROCHLORIDE ()
CP-19106-1 ()
CP-19,106-1 ()
P&D ID
PD004140
CAS
35795-16-5
53746-46-6
Tags
available
drug candidate
drug
Drug indication
Congestive heart failure
Antihypertensive
Drug Status
experimental
approved
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Trimazosin hydrochloride is a sympatholytic alpha blocker. It is used in the treatment of hypertensive patients failing to respond to thiazides. It is useful in therapy as potent antihypertensive agents.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
10
BOC Sciences Bioactive Compounds
ChEMBL Drugs
DrugBank
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
DrugMatrix
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
24
Molecular Weight
435.21
Hydrogen Bond Acceptors
10
Hydrogen Bond Donors
2
Rotatable Bonds
6
Ring Count
3
Aromatic Ring Count
2
cLogP
1.27
TPSA
132.5
Fraction CSP3
0.55
Chiral centers
0.0
Largest ring
6.0
QED
0.68
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Member status
member
MOA
alpha-Adrenoceptor Antagonists
Solubility
Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Source data
