General
Preferred name
TRIPTOLIDE
Synonyms
P&D ID
PD003701
Tags
natural product
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
natural product; inhibitor of RNA polymerase II
(Informer Set)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
3
Informer Set
Mcule NIBR MoA Box Subset
Novartis Chemogenetic Library (NIBR MoA Box)
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
8
Molecular Weight
360.16
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
1
Rotatable Bonds
1
Ring Count
7
Aromatic Ring Count
0
cLogP
1.1
TPSA
84.12
Fraction CSP3
0.85
Chiral centers
9.0
Largest ring
6.0
QED
0.56
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Compound status
clinical
Member status
member
MOA
ERCC3 (TFIIH subunit)
Source data
