General
Preferred name
BMS614
Synonyms
BMS-195614 ()
BMS 195614 ()
P&D ID
PD003651
CAS
182135-66-6
Tags
available
drug candidate
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION antagonist of retinoic acid receptors (Informer Set)
DESCRIPTION Selective Rev-Erbalpha agonist (Tocris Bioactive Compound Library)
Compound Sets
5
Cayman Chemical Bioactives
16029
DrugMAP
DMZWNO9
Guide to Pharmacology
2643
Informer Set
660228
Tocris Bioactive Compound Library
3660
External IDs
12
Properties
(calculated by RDKit )
Molecular Weight
448.18
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
5
Aromatic Ring Count
4
cLogP
6.3
TPSA
79.29
Fraction CSP3
0.14
Chiral centers
0.0
Largest ring
6.0
QED
0.38
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Target
RARA
RARB
RARG
Compound status
probe
Primary Target
Retinoic Acid Receptors
MOA
Antagonist
Source data