General
Preferred name
NVP-BSK805
Synonyms
BSK805 dihydrochloride ()
BSK 805 ()
NVP BSK 805 ()
NVP-BSK805 2HCl (1092499-93-8(free base)) ()
NVP-BSK805 2HCl ()
NVP-BSK805 (dihydrochloride) ()
Nvp-bsk805 dihydrochloride ()
BSK805 ()
?NVP-BSK805 (hydrochloride) ()
P&D ID
PD003577
CAS
1092499-93-8
1942919-79-0
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
inhibitor of Janus kinase 2
(Informer Set)
DESCRIPTION
Potent and selective PI 3-kinase beta inhibitor
(Tocris Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
12
AdooQ Bioactive Compound Library
Axon Medchem Screening Library
Cayman Chemical Bioactives
CZ-OPENSCREEN Bioactive Library
Drug Repurposing Hub
Informer Set
Mcule NIBR MoA Box Subset
Novartis Chemogenetic Library (NIBR MoA Box)
Selleckchem Bioactive Compound Library
Tocris Bioactive Compound Library
ZINC Tool Compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
26
Molecular Weight
490.23
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
1
Rotatable Bonds
5
Ring Count
6
Aromatic Ring Count
4
cLogP
4.2
TPSA
68.1
Fraction CSP3
0.37
Chiral centers
0.0
Largest ring
6.0
QED
0.45
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
JAK2
JAK2 inhibitor
Compound status
probe
Primary Target
JAK Kinase
MOA
JAK
Inhibitor
Jak2 Inhibitors
JAK inhibitor
Pathway
Tyrosine Kinase/Adaptors
Angiogenesis
Chromatin/Epigenetic
Stem Cells
Epigenetics
JAK/STAT Signaling
Protein Tyrosine Kinase/RTK
Stem Cell/Wnt
Member status
member
Source data
