General
Preferred name
norethisterone
Synonyms
CPD000499579 ()
NORETHINDRONE ()
19-Norethindrone ()
Triella ()
SC-4640 ()
Norethisteronum ()
Aygestin ()
Norethidrone ()
Calluna vulgaris whole ()
Norlutin ()
Norethisterone ()
Norethisteron ()
Heather ()
Femhrt ()
Gestest ()
Micronor HRT ()
Primolut N ()
Menzol ()
Combipatch ()
Camila ()
Incassia ()
NSC-9564 ()
Micronor ()
Anovule ()
Heather whole ()
Activella ()
Jencycla ()
Nor-Qd ()
Noriday ()
Utovlan ()
Errin ()
Calluna vulgaris ()
Norlutate ()
Norethindrone-d6 ()
P&D ID
PD003185
CAS
68-22-4
2376036-05-2
Tags
natural product
drug
available
Approved by
FDA
First approval
1962
Drug Status
approved
Drug indication
Progestin
Solid tumour/cancer
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION A synthetic progestational hormone but more potently inhibits ovulation than does progesterone.
Marketed formulations may contain norethisterone acetate (PubChem CID 5832). (GtoPdb)
Compound Sets
21
Bioprocess diversity set
Cayman Chemical Bioactives
20941
33277
ChEMBL Approved Drugs
CHEMBL1162
ChEMBL Drugs
CHEMBL1162
Drug Repurposing Hub
DrugBank
DB00717
DrugBank Approved Drugs
DB00717
DrugCentral
1962
DrugCentral Approved Drugs
1962
DrugMAP
DMTY169
DrugMAP Approved Drugs
DMTY169
Guide to Pharmacology
2880
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL1162
MedChem Express Bioactive Compound Library
HY-B0554
NCATS Inxight Approved Drugs
T18F433X4S
NIH Clinical Collections (NCC)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
norethindrone-norethisterone
TargetMol Bioactive Compound Library
T1514
External IDs
47
Properties
(calculated by RDKit )
Molecular Weight
298.19
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
0
Ring Count
4
Aromatic Ring Count
0
cLogP
3.49
TPSA
37.3
Fraction CSP3
0.75
Chiral centers
6.0
Largest ring
6.0
QED
0.7
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Biological process
Peroxisome
Pathway
Endocrinology/Hormones
Anti-infection
Vitamin D Related/Nuclear Receptor
Target
ER
PGR
Bacterial
Progesterone Receptor
Others,0
Indication
endometriosis
MOA
Progesterone receptor agonist
Therapeutic Class
Contraceptive Agents
Source data