General
Preferred name
MAFENIDE ACETATE
Synonyms
Mafenide (Acetate) ()
Sulfamylon ()
P&D ID
PD003172
CAS
13009-99-9
Tags
available
drug
Drug Status
approved
Max Phase
4.0
Drug indication
osteomyelitis
First approval
1969
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Mafenide Acetate is an effective sulfonamide-type antimicrobial agent used for burn wounds. Mafenide Acetate shows activity against both Gram-positive and Gram-negative organisms, including Pseudomonas aeruginosa, via inhibition of nucleotide synthesis[1][2].
PRICE 80
DESCRIPTION Mafenide is a bacteriostatic antibiotic with a broad activity against Gram positive, Gram negative bacteria and Clostridia. Mafenide acetate penetrates eschar and prevents heavy colonization in burn wounds. (BOC Sciences Bioactive Compounds)
DESCRIPTION Mafenide Acetate is a sulfonamide-type medication inhibits the enzyme carbonic anhydrase and is used as topical anti-infective, especially in burn therapy. (TargetMol Bioactive Compound Library)
Compound Sets
7
BOC Sciences Bioactive Compounds
mafenide-acetate-cas-13009-99-9-56920
ChEMBL Approved Drugs
CHEMBL1201161
ChEMBL Drugs
CHEMBL1201161
MedChem Express Bioactive Compound Library
HY-B0614A
NIH Clinical Collections (NCC)
Selleckchem Bioactive Compound Library
mafenide-acetate
TargetMol Bioactive Compound Library
T8122
External IDs
18
Properties
(calculated by RDKit )
Molecular Weight
246.07
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
3
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
1
cLogP
-0.12
TPSA
123.48
Fraction CSP3
0.22
Chiral centers
0.0
Largest ring
6.0
QED
0.67
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
antibiotic
Bacterial
Fungal
Carbonic Anhydrase
Pathway
Microbiology/virology
Anti-infection
Solubility
Soluble in DMSO
Source data