General
Preferred name
Mexamine, Methoxytryptamine
Synonyms
MEXAMINE ()
O-Methylserotonin hydrochloride ()
5-METHOXYTRYPTAMINE ()
2-(5-methoxy-1H-indol-3-yl)ethan-1-amine ()
5-MeOT ()
5-methoxy Tryptamine (hydrochloride) ()
5-methoxy Tryptamine-d4 ()
P&D ID
PD003168
CAS
66-83-1
17107-33-4
608-07-1
96236-05-4
Tags
available
drug candidate
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Nonselective serotonin receptor agonist that lacks affinity for the 5-HT3 receptor
(LOPAC library)
DESCRIPTION
5-Methoxytryptamine is a tryptamine derivative that acts as a full agonist at the 5-HT1, 5-HT2, 5-HT4, 5-HT6, and 5-HT7 receptors.
(BOC Sciences Bioactive Compounds)
DESCRIPTION
5-Methoxytryptamine is a tryptamine derivative that acts as a full agonist at the 5-HT1, 5-HT2, 5-HT4, 5-HT6, and 5-HT7 receptors.
(Enamine Bioactive Compounds)
DESCRIPTION
Agonist activity at 5HT2A receptor (unknown origin) by cell based calcium mobilization assay; Binding affinity at rat 5-hydroxytryptamine 7 receptor.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
12
BOC Sciences Bioactive Compounds
DrugMAP
Enamine Bioactive Compounds
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
Ki Database
LOPAC library
NIH Clinical Collections (NCC)
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
The Spectrum Collection
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
53
Molecular Weight
190.11
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
2
cLogP
1.68
TPSA
51.04
Fraction CSP3
0.27
Chiral centers
0.0
Largest ring
6.0
QED
0.77
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
5-HT Receptor
Source data
