General
Preferred name
TRIAMCINOLONE ACETONIDE
Synonyms
Aristogel ()
Azmacort ()
Aristoderm ()
Triamcinolone acetonide-d7 ()
Kenalog-40 ()
Xipere ()
Flutex ()
Silderm ()
Tri-Nasal ()
Volonimat ()
Gppe Ear Oint ()
Vetalog ()
Kenalog In Orabase ()
FX-006 ()
Aureocort ()
Ledercort cream ()
Kenalog-80 ()
Adcortyl In Orabase ()
Oracort ()
Zilretta ()
Aristocort ()
Nystadermal ()
Audicort ()
Nasacort Hfa ()
Kenacourt ()
Volon a ()
Tramacin ()
Solodelf ()
NSC-21916 ()
Gppe Ear Dps Cap ()
Remiderm ()
Remotic ()
Respicort ()
Tricinolon ()
Rineton ()
Triamcinolone acetonide component of mycolog ()
Kenalog-H ()
Trymex ()
Nasacort ()
Trivaris ()
Allernaze ()
Kenalog-10 ()
Triamcinolone Acetonide In Absorbase ()
Ftorocort ()
Triderm ()
Triam ()
Extracort ()
Triesence ()
Nasacort Aq ()
FX006 ()
Kenalog ()
Pevaryl T.C. ()
Kenacort-a ()
Adcortyl ()
Oralone ()
Triamcinolone acetonide component of mytrex f ()
Triamcinolone acetonide component of mytrex a ()
Tri-Adcortyl ()
Triamcinolone acetonide component of mykacet ()
Triacet ()
Nasacort allergy 24 hour ()
Triatex ()
Triacort ()
Aristocort A ()
P&D ID
PD003160
CAS
76-25-5
13586-95-3
Tags
available
probe
drug
Approved by
FDA
First approval
1960
Drug Status
vet_approved
approved
Max Phase
4.0
Drug indication
Diabetic retinopathy
Probe info
Probe type
calculated probe
Probe sources
Probe Miner (suitable probes)
Probe targets
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION The approved drug often contains this formulation of the compound.
DESCRIPTION Triamcinolone is a corticosteroid type anti-inflammatory drug. The approved drug often contains this formulation of the compound. The hexacetonide, furetonide and benetonide forms all have individual INNs. (GtoPdb)
PRICE 29
DESCRIPTION Triamcinolone acetonide inhibits basic fibroblast growth factor (bFGF) induced proliferation of retinal endothelial cells. Triamcinolone acetonide reduces chondrocyte viability and leads to cartilage destruction. Triamcinolone acetonide activates macrophage with anti-inflammatory characteristics. Triamcinolone acetonide can be used in the study of diseases such as atopic dermatitis[1][2][3][4].
DESCRIPTION Triamcinolone acetonide (Azmacort) is a Corticosteroid. The mechanism of action of triamcinolone acetonide is as a Corticosteroid Hormone Receptor Agonist. It is an anti-inflammatory glucocorticoid used topically in the treatment of various skin disorders. Intralesional, intramuscular, and intra-articular injections are also administered under certain conditions. (TargetMol Bioactive Compound Library)
Cell lines
1
Organisms
1
Compound Sets
17
Cayman Chemical Bioactives
18026
25236
ChEMBL Approved Drugs
CHEMBL1504
ChEMBL Drugs
CHEMBL1504
Drug Repurposing Hub
DrugCentral
2726
DrugCentral Approved Drugs
2726
Guide to Pharmacology
2867
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL1504
MedChem Express Bioactive Compound Library
HY-B0636
NCATS Inxight Approved Drugs
F446C597KA
NIH Clinical Collections (NCC)
NPC Screening Collection
NURSA ligand set
nursa/index.jsf?doi=10.1621%2FMZYZDF1U4V
Probe Miner (suitable probes)
P04150/331914
ReFrame library
Selleckchem Bioactive Compound Library
Triamcinolone-Acetonide
TargetMol Bioactive Compound Library
T0820
External IDs
59
Properties
(calculated by RDKit )
Molecular Weight
434.21
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
5
Aromatic Ring Count
0
cLogP
2.42
TPSA
93.06
Fraction CSP3
0.75
Chiral centers
8.0
Largest ring
6.0
QED
0.69
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Glucocorticoid Receptor
NR3C1, SERPINA6
FGFR
Indication
corticosteroid-responsive dermatoses
MOA
glucocorticoid receptor agonist, immunosuppressant
Pathway
Immunology/Inflammation
Protein Tyrosine Kinase/RTK
Vitamin D Related/Nuclear Receptor
Endocrinology/Hormones
Source data