General
Preferred name
miglitol
Synonyms
BAY-m1099 ()
BAY1099 ()
Miglitol (Glyset) ()
Diastabol ()
BAY-M-1099,Glyset ()
BAY-M-1099 ()
Glyset ()
BAY M 1099 ()
NSC-758702 ()
Miglitol-d4 ()
P&D ID
PD003092
CAS
1204250-58-7
72432-03-2
Tags
natural product
drug
available
Approved by
FDA
First approval
1996
Drug Status
approved
Drug indication
Diabetic complication
Inhibitor (alpha-glucosidase)
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Miglitol is an iminosugar type drug which inhibits alpha-glucosidase as a mechanism to improve glycemic control in type II diabetics.
(GtoPdb)
DESCRIPTION
Type 1 BMP receptor inhibitor
(Tocris Bioactive Compound Library)
DESCRIPTION
alpha-glucosidase inhibitor
(Tocriscreen Plus)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
33
AdooQ Bioactive Compound Library
Axon Medchem Screening Library
CeMM library of unique drugs (CLOUD)
ChEMBL Approved Drugs
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Enamine BioReference Compounds
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
Natural product-based probes and drugs
NCATS Inxight Approved Drugs
NIH Clinical Collections (NCC)
Novartis Chemogenetic Library (NIBR MoA Box)
NPC Screening Collection
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
Tocris Bioactive Compound Library
Tocriscreen Plus
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
43
Molecular Weight
207.11
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
5
Rotatable Bonds
3
Ring Count
1
Aromatic Ring Count
0
cLogP
-3.26
TPSA
104.39
Fraction CSP3
1.0
Chiral centers
4.0
Largest ring
6.0
QED
0.33
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target Type
Enzymes
MOA
alpha glucosidase inhibitor
Inhibitor
SGLT-3 Activators
alpha-Glucosidase Inhibitors
glucosidase inhibitor
Target
Lysosomal alpha-glucosidase
Maltase-glucoamylase
GAA
MGA
GAA, GANAB, GANC, MGAM
Glucosidase inhibitor
Carbohydrate Metabolism
Primary Target
Glycosylases
Member status
member
Indication
diabetes mellitus
Biosynthetic Origin
Carbohydrate
Therapeutic Indication
Antidiabetic
Therapeutic Class
Metabolic Disorders
Hypoglycemic Agents
Source data
