General
Preferred name
Milnacipran HCl
Synonyms
Savella ()
Dalcipran ()
MILNACIPRAN HYDROCHLORIDE ()
Milnacipran (hydrochloride) ()
1R,2S-MILNACIPRAN HYDROCHLORIDE ()
P&D ID
PD003091
CAS
86181-08-0
101152-94-7
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Milnacipran is a serotonin-norepinephrine reuptake inhibitor (SNRI) used for fibromyalgia.
PRICE 29
DESCRIPTION Milnacipran hydrochloride (Savella) is a serotonin and norepinephrine reuptake inhibitor used to treat major depressive disorders. Milnacipran hydrochloride is an enantiomer of milnacipran, which is used to treat fibromyalgia. Milnacipran hydrochloride and milnacipran have been associated with a low rate of transient elevations in serum aminotransferase levels during treatment and with rare instances of clinically apparent acute liver injury with jaundice. (TargetMol Bioactive Compound Library)
Compound Sets
7
Cayman Chemical Bioactives
23837
EU-OPENSCREEN Bioactive Compound Library
EOS101255
MedChem Express Bioactive Compound Library
HY-B0168A
NIH Clinical Collections (NCC)
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
milnacipran-hydrochloride
TargetMol Bioactive Compound Library
T1189
External IDs
23
Properties
(calculated by RDKit )
Molecular Weight
282.15
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
5
Ring Count
2
Aromatic Ring Count
1
cLogP
2.19
TPSA
46.33
Fraction CSP3
0.53
Chiral centers
2.0
Largest ring
6.0
QED
0.9
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Neuroscience
Cell Cycle/DNA Damage
Neuronal Signaling
Target
PERK
Serotonin Transporter
norepinephrine transporter (NET)
norepinephrine transporter (SERT)
Source data