General
Preferred name
DESOXIMETASONE
Synonyms
Desoxymethasone ()
Desoximetasonum ()
Topicort ()
Desoximetasona ()
D¨¦soxim¨¦tasone ()
Desoxymethasone, Desoximetasonum ()
NSC-759189 ()
HOE 304 ()
Topicort Lp ()
A-41304 ()
J83.644C ()
Stiedex LP ()
R-2113 ()
Stiedex LPN ()
R 2113 ()
HOE-304 ()
A-41-304 ()
Stiedex ()
Desoximetasone-d3 ()
P&D ID
PD003028
CAS
382-67-2
140218-14-0
Tags
natural product
drug
available
Approved by
FDA
First approval
1977
Drug Status
approved
Drug indication
Inflammation
Anti-Inflammatory
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Desoximetasone is a corticosteroid. (GtoPdb)
Compound Sets
20
Cayman Chemical Bioactives
23945
28159
ChEMBL Approved Drugs
CHEMBL1766
ChEMBL Drugs
CHEMBL1766
Drug Repurposing Hub
DrugBank
DB00547
DrugBank Approved Drugs
DB00547
DrugCentral
819
DrugCentral Approved Drugs
819
DrugMAP
DM4PXF6
DrugMAP Approved Drugs
DM4PXF6
EU-OPENSCREEN Bioactive Compound Library
EOS101314
Guide to Pharmacology
7067
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL1766
MedChem Express Bioactive Compound Library
HY-17570
NCATS Inxight Approved Drugs
4E07GXB7AU
NIH Clinical Collections (NCC)
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
desoximetasone
TargetMol Bioactive Compound Library
T4572
External IDs
35
Properties
(calculated by RDKit )
Molecular Weight
376.2
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
4
Aromatic Ring Count
0
cLogP
2.78
TPSA
74.6
Fraction CSP3
0.73
Chiral centers
8.0
Largest ring
6.0
QED
0.78
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Indication
corticosteroid-responsive dermatoses
Target
NR3C1, PLA2G1B
Glucocorticoid Receptor
MOA
Glucocorticoid Receptor agonist
Therapeutic Class
Antiinflammatory Agents
Source data