General
Preferred name
DESOXIMETASONE
Synonyms
Desoximetasonum ()
Topicort ()
Desoxymethasone ()
Desoximetasona ()
D¨¦soxim¨¦tasone ()
Desoxymethasone, Desoximetasonum ()
HOE-304 ()
J83.644C ()
HOE 304 ()
R 2113 ()
R-2113 ()
A-41304 ()
Stiedex LPN ()
Topicort Lp ()
NSC-759189 ()
A-41-304 ()
Stiedex ()
Stiedex LP ()
Desoximetasone-d3 ()
P&D ID
PD003028
CAS
382-67-2
140218-14-0
Tags
available
drug
Approved by
FDA
First approval
1977
Drug indication
psoriasis
Inflammation
Drug Status
approved
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Desoximetasone is a corticosteroid.
(GtoPdb)
PRICE
29
DESCRIPTION
Desoximetasone is a corticosteroid and a substrate of cytochrome P450 3A4. Desoximetasone has anti-inflammatory, anti-allergic, and immunosuppressive effects. Desoximetasone can be used in the research of various skin diseases, such as skin allergies, atopic dermatitis, and psoriasis[1][2].
DESCRIPTION
Desoximetasone (Desoximetasona)(Topicort), a topical corticosteroid, is employed for the alleviation of diverse skin conditions, including rashes.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
20
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
NIH Clinical Collections (NCC)
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
39
Molecular Weight
376.2
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
4
Aromatic Ring Count
0
cLogP
2.78
TPSA
74.6
Fraction CSP3
0.73
Chiral centers
8.0
Largest ring
6.0
QED
0.78
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Indication
corticosteroid-responsive dermatoses
Target
NR3C1, PLA2G1B
Cytochrome P450
Glucocorticoid Receptor
Interleukin Related
MOA
Glucocorticoid Receptor agonist
Therapeutic Class
Antiinflammatory Agents
Pathway
Immunology/Inflammation
Metabolic Enzyme/Protease
Vitamin D Related/Nuclear Receptor
Source data
