General
Preferred name
flunisolide
Synonyms
Rhinalar ()
Synaclyn ()
Aerobid ()
FLUNISOLIDE ANHYDROUS ()
Aerospan ()
RS-3999 ()
Nasarel ()
NSC-757871 ()
Syntaris ()
Aerospan hfa ()
Flunisolide hemihydrate ()
Nasalide ()
Syntaris Hayfever ()
P&D ID
PD002992
CAS
3385-03-3
Tags
natural product
drug
available
Approved by
FDA
First approval
1981
Drug Status
investigational
approved
Drug indication
Allergic rhinitis
Glucocorticoid
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Flunisolide is a corticosteroid.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
22
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
NIH Clinical Collections (NCC)
NPC Screening Collection
Prestwick Chemical Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
43
Molecular Weight
434.21
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
5
Aromatic Ring Count
0
cLogP
2.27
TPSA
93.06
Fraction CSP3
0.75
Chiral centers
9.0
Largest ring
6.0
QED
0.69
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolism
Apoptosis
Immunology/Inflammation
Vitamin D Related/Nuclear Receptor
Target
Glucocorticoid Receptor
NR3C1
Indication
allergic rhinitis
MOA
Cytochrome P450 inhibitor
Therapeutic Class
Antiasthmatic Agents
Source data
