General
Preferred name
Galanthamine hydrobromide
Synonyms
GALANTAMINE HYDROBROMIDE ()
Galanthamine HBr ()
Galantamine HBr ()
Galanthamine (hydrobromide) ()
Galantamine (hydrobromide) ()
Razadyne ER ()
Jilkon hydrobromide ()
Nivalin ()
Razadyne ()
(-)-galantamine hydrobromide ()
Nivaline ()
Lycoremine hydrobromide ()
Tamilin ()
P&D ID
PD002984
CAS
1953-04-4
69353-21-5
Tags
natural product
drug
available
Drug Status
approved
Max Phase
Phase 4
First approval
2001
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION MAO-A inhibitor (Tocris Bioactive Compound Library)
DESCRIPTION Cholinesterase inhibitor (Tocriscreen Total)
Compound Sets
14
AdooQ Bioactive Compound Library
A10416
Cayman Chemical Bioactives
35247
ChEMBL Approved Drugs
CHEMBL1555
ChEMBL Drugs
CHEMBL1555
Enamine BioReference Compounds
EU-OPENSCREEN Bioactive Compound Library
EOS101393
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL1555
MedChem Express Bioactive Compound Library
HY-A0009
NIH Clinical Collections (NCC)
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
Galanthamine-hydrobromide
TargetMol Bioactive Compound Library
T0086
Tocris Bioactive Compound Library
0686
Tocriscreen Total
External IDs
29
Properties
(calculated by RDKit )
Molecular Weight
367.08
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
1
Ring Count
4
Aromatic Ring Count
1
cLogP
2.43
TPSA
41.93
Fraction CSP3
0.53
Chiral centers
3.0
Largest ring
7.0
QED
0.77
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Neuroscience
Membrane Transporter/Ion Channel
Neuronal Signaling
Target
AChE
Apoptosis
Cholinesterase (ChE)
nAChR
AChR,ADC Cytotoxin
Primary Target
Cholinesterases
MOA
Inhibitor
Source data