General
Preferred name
VECURONIUM BROMIDE
Synonyms
Vecuronium (bromide) ()
ORG NC 45 ()
ORG NC45 ()
Vecuronium (bromide) ()
Norcuron ()
Musculax ()
Pancuronium bromide impurity, vecuronium bromide - ()
Bromuro de vecuronio ()
NSC-759184 ()
Bromure de vecuronium ()
ORG-NC 45 ()
P&D ID
PD002954
CAS
50700-72-6
Tags
available
drug
Drug Status
approved
Max Phase
4.0
First approval
1984
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Vecuronium (ORG NC 45) bromide is a non-depolarizing neuromuscular blocking agent that also acts as a nicotinic acetylcholine receptor (nAChR) inhibitor, a muscle relaxant, and can be used for pre-surgical anesthesia[1][2].
DESCRIPTION
Vecuronium is a nondepolarizing neuromuscular blocking agent used to relax muscles or as an adjunct in general anesthesia during surgical procedures.
(Enamine Bioactive Compounds)
DESCRIPTION
Vecuronium bromide (Norcuron) is a muscle relaxant in the category of non-depolarizing blocking agents. Vecuronium bromide is indicated as an adjunct to general anesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Although vecuronium bromide is often thought of as a muscle relaxant, it may be more accurate to classify it as a paralyzing agent.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
13
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
CeMM library of unique drugs (CLOUD)
ChEMBL Approved Drugs
ChEMBL Drugs
CZ-OPENSCREEN Bioactive Library
Enamine Bioactive Compounds
Enamine BioReference Compounds
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
NIH Clinical Collections (NCC)
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
21
Molecular Weight
636.35
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
0
Rotatable Bonds
4
Ring Count
6
Aromatic Ring Count
0
cLogP
2.97
TPSA
55.84
Fraction CSP3
0.94
Chiral centers
10.0
Largest ring
6.0
QED
0.35
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
nicotinic acetylcholine receptor antagonist
AChR
Target
Muscle-type nicotinic acetylcholine receptor
nAChR
Pathway
Membrane Transporter/Ion Channel
Neuronal Signaling
Source data
