General
Preferred name
VECURONIUM BROMIDE
Synonyms
ORG NC 45 ()
Vecuronium (bromide) ()
ORG NC45 ()
Pancuronium bromide impurity, vecuronium bromide - ()
Norcuron ()
NSC-759184 ()
ORG-NC 45 ()
Musculax ()
Vecuronium (bromide) ()
P&D ID
PD002954
CAS
50700-72-6
Tags
available
drug
Drug Status
approved
Max Phase
Phase 4
Drug indication
Neuromuscular Blocking Agent
First approval
1984
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Vecuronium bromide (Norcuron) is a muscle relaxant in the category of non-depolarizing blocking agents. Vecuronium bromide is indicated as an adjunct to general anesthesia, to facilitate endotracheal intubation and to provide skeletal muscle relaxation during surgery or mechanical ventilation. Although vecuronium bromide is often thought of as a muscle relaxant, it may be more accurate to classify it as a paralyzing agent.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
12
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
CeMM library of unique drugs (CLOUD)
ChEMBL Approved Drugs
ChEMBL Drugs
Enamine BioReference Compounds
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
NIH Clinical Collections (NCC)
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
19
Molecular Weight
636.35
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
0
Rotatable Bonds
4
Ring Count
6
Aromatic Ring Count
0
cLogP
2.97
TPSA
55.84
Fraction CSP3
0.94
Chiral centers
10.0
Largest ring
6.0
QED
0.35
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
MOA
nicotinic acetylcholine receptor antagonist
AChR
Target
Muscle-type nicotinic acetylcholine receptor
nAChR
Pathway
Neuroscience
Membrane Transporter/Ion Channel
Neuronal Signaling
Source data
