General
Preferred name
PREDNISOLONE ACETATE
Synonyms
Omnipred ()
Prednisolone-21-acetate ()
Prednisolone 21-acetate ()
Omnipred,Prednisolone-21-acetate ()
Meticortelone ()
Econopred ()
Pred Mild ()
Ultracortenol ()
Prednisoloni acetas ()
Pred Fte ()
NSC-10966 ()
Sterane ()
Pred Forte ()
Flo-Pred ()
P&D ID
PD002903
CAS
52-21-1
Tags
prodrug
natural product
drug
available
Approved by
FDA
First approval
1955
Drug Status
approved
vet_approved
Max Phase
Phase 4
Drug indication
Glucocorticoid
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
14
AdooQ Bioactive Compound Library
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
MedChem Express Bioactive Compound Library
NIH Clinical Collections (NCC)
NPC Screening Collection
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
40
Properties
(calculated by RDKit )
Molecular Weight
402.2
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
2
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
0
cLogP
2.13
TPSA
100.9
Fraction CSP3
0.7
Chiral centers
7.0
Largest ring
6.0
QED
0.7
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolism
Immunology/Inflammation
Vitamin D Related/Nuclear Receptor
Target
Glucocorticoid Receptor
NR3C1
Disease Area
ophthalmology, dermatology, infectious disease
Indication
conjunctivitis, rosacea, punctate keratitis, shingles, iritis, cyclitis
MOA
Glucocorticoid Receptor agonist
Source data
