General
Preferred name
prednisone
Synonyms
Prednisone (Adasone) ()
Prednisone53-03-2 ()
Dehydrocortisone ()
Adasone,NSC-10023 ()
Prednisone (NSC-10023) ()
Deltasone ()
Metacortandracin ()
3en3hg4wsw ()
Prednicen-M ()
Decortin ()
Prednisone anhydrous ()
Prednisone tablets ()
Delta-Dome ()
Orasone ()
Rayos ()
Lodotra ()
Prednisone Intensol ()
Meticorten ()
Supercortil ()
NSC-10023 ()
Paracort ()
Liquid Pred ()
Fernisone ()
Prednisona ()
Servisone ()
Sterapred ()
Decortisyl ()
Cortan ()
Cortancyl ()
Prednisone-d7 ()
P&D ID
PD002901
CAS
13479-38-4
53-03-2
Tags
available
prodrug
drug
Approved by
FDA
First approval
1955
Drug indication
Nasal Cavity Polyp
Eczema
Atopic dermatitis
Inflammation
Drug Status
vet_approved
approved
Max Phase
4.0
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Prednisone is a synthetic corticosteroid. (GtoPdb)
PRICE 29
DESCRIPTION Prednisone (Adasone) is a corticosteroid agent with anti-inflammatory and immunosuppressive effects that can be used to study diseases related to systemic lupus erythematosus[1][2].
DESCRIPTION Prednisone (Dehydrocortisone) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.
DESCRIPTION Prednisone is a corticosteroid used to treat inflammation or immune-mediated reactions. (Enamine Bioactive Compounds)
Cell lines
1
Organisms
0
Compound Sets
22
AdooQ Bioactive Compound Library
A10752
Cayman Chemical Bioactives
20677
26459
ChEMBL Approved Drugs
CHEMBL635
ChEMBL Drugs
CHEMBL635
Drug Repurposing Hub
DrugBank
DB00635
DrugBank Approved Drugs
DB00635
DrugCentral
2253
DrugCentral Approved Drugs
2253
DrugMAP
DM2HG4X
DrugMAP Approved Drugs
DM2HG4X
Enamine Bioactive Compounds
EBC-26720
Guide to Pharmacology
7096
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL635
MedChem Express Bioactive Compound Library
HY-B0214
NCATS Inxight Approved Drugs
VB0R961HZT
NIH Clinical Collections (NCC)
NPC Screening Collection
NURSA ligand set
nursa/index.jsf?doi=10.1621%2F4P236M7QYY
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
Prednisone
External IDs
59
Properties
(calculated by RDKit )
Molecular Weight
358.18
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
4
Aromatic Ring Count
0
cLogP
1.77
TPSA
91.67
Fraction CSP3
0.67
Chiral centers
6.0
Largest ring
6.0
QED
0.78
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Disease Area
endocrinology, rheumatology, infectious disease, dermatology, ophthalmology, hematology, gastroenterology, neurology/psychiatry
Indication
congenital adrenal hyperplasia, hypercalcemia, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, bursitis, osteoarthritis, epicondylitis, dermatomyositis, psoriasis, mycosis, conjunctivitis, anemia, ulcerative colitis, enteritis, multiple sclerosis, meningitis
Target
HSD11B1, NR3C1
Apoptosis
Glucocorticoid Receptor
Glucocorticoid Receptor,Immunology & Inflammation related
MOA
Glucocorticoid Receptor agonist
Therapeutic Class
Antiinflammatory Agents
Pathway
Immunology/Inflammation
Vitamin D Related/Nuclear Receptor
Source data