General
Preferred name
prednisone
Synonyms
Dehydrocortisone ()
Prednisone (Adasone) ()
Prednisone53-03-2 ()
Prednisone (NSC-10023) ()
Adasone,NSC-10023 ()
Liquid Pred ()
Supercortil ()
Prednisone tablets ()
Deltasone ()
Meticorten ()
Prednisone Intensol ()
Delta-Dome ()
Prednicen-M ()
Decortisyl ()
Prednisone anhydrous ()
Servisone ()
Orasone ()
Paracort ()
NSC-10023 ()
Decortin ()
Cortan ()
Sterapred ()
Metacortandracin ()
Fernisone ()
Cortancyl ()
Lodotra ()
Rayos ()
3en3hg4wsw ()
Prednisone-d7 ()
P&D ID
PD002901
CAS
13479-38-4
53-03-2
Tags
prodrug
natural product
drug
available
Approved by
FDA
First approval
1955
Drug Status
approved
vet_approved
Drug indication
Inflammation
Eczema
Atopic dermatitis
Glucocorticoid
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Prednisone is a synthetic corticosteroid.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
0
Compound Sets
22
AdooQ Bioactive Compound Library
ChEMBL Approved Drugs
ChEMBL Drugs
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
MedChem Express Bioactive Compound Library
NCATS Inxight Approved Drugs
NIH Clinical Collections (NCC)
NPC Screening Collection
NURSA ligand set
Prestwick Chemical Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
55
Molecular Weight
358.18
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
4
Aromatic Ring Count
0
cLogP
1.77
TPSA
91.67
Fraction CSP3
0.67
Chiral centers
6.0
Largest ring
6.0
QED
0.78
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Immunology/Inflammation
Metabolism
Apoptosis
Vitamin D Related/Nuclear Receptor
Target
Glucocorticoid Receptor
MRP1
HSD11B1, NR3C1
Glucocorticoid Receptor,Immunology & Inflammation related
Disease Area
endocrinology, rheumatology, infectious disease, dermatology, ophthalmology, hematology, gastroenterology, neurology/psychiatry
Indication
congenital adrenal hyperplasia, hypercalcemia, rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, bursitis, osteoarthritis, epicondylitis, dermatomyositis, psoriasis, mycosis, conjunctivitis, anemia, ulcerative colitis, enteritis, multiple sclerosis, meningitis
MOA
Glucocorticoid Receptor agonist
Therapeutic Class
Antiinflammatory Agents
Source data
